منابع مشابه
Genomic tics in tourette syndrome.
1 I t is a striking observation that studies of copy number variation (CNV) in neurodevelopmental phenotypes continue to report an excess of rare variants in case populations. This astonishing esult has been observed and replicated in studies of intellectual isability (1), autism (2), schizophrenia (3), and epilepsy (4). In a tudy published this month in Biological Psychiatry, Tourette synrome ...
متن کاملTics and Tourette syndrome: an adult perspective.
Tourette syndrome (TS) is a disorder characterized by childhood onset multiple motor and vocal tics often accompanied by features of obsessive compulsive disorder, attention deficit hyperactivity disorder (ADHD), or other behavioral manifestations. Tics may be simple or complex, and may include motor and vocal components. Abnormal function of the basal ganglia is thought to be an important unde...
متن کاملTreatment strategies for tics in Tourette syndrome.
TOURETTE SYNDROME (TS) IS A CHRONIC NEURODEVELOPMENTAL DISORDER CHARACTERIZED BY TICS: repetitive, involuntary movements and vocalizations. These symptoms can have a significant impact on patients' daily functioning across many domains. Tics tend to be most severe in child and adolescent sufferers, so their presence has the potential to impact a period of life that is both critical for learning...
متن کاملDeutetrabenazine in Tics Associated with Tourette Syndrome
BACKGROUND Deutetrabenazine, an inhibitor of vesicular monoamine transporter type 2 (VMAT2) depletes presynaptic dopamine and is useful in the treatment of hyperkinetic movement disorders. This study explored the safety, tolerability, and preliminary efficacy of deutetrabenazine in adolescents with moderate-to-severe tics associated with Tourette syndrome (TS). METHODS In this open-label stud...
متن کاملOlanzapine in Gilles de la Tourette syndrome: beyond tics.
UNLABELLED Although there only have been a limited number of double-blind, placebo controlled trials, antipsychotics are considered to be effective drugs for the treatment of tics in Gilles de la Tourette syndrome (GTS). Evidence concerning the efficacy of olanzapine and other atypical antipsychotics in the treatment of tics in GTS is growing, but still limited. Little is known about the use of...
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ژورنال
عنوان ژورنال: Drugs in Context
سال: 2020
ISSN: 1740-4398
DOI: 10.7573/dic.2019-12-2